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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAMKK2
All Species:
19.09
Human Site:
S495
Identified Species:
46.67
UniProt:
Q96RR4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RR4
NP_006540.3
588
64732
S495
K
T
M
I
R
K
R
S
F
G
N
P
F
E
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093436
588
64878
S495
K
T
M
I
R
K
R
S
F
G
N
P
F
E
G
Dog
Lupus familis
XP_543388
578
63709
S487
K
T
M
I
R
K
R
S
F
G
N
P
F
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8C078
588
64599
S495
K
T
M
I
R
K
R
S
F
G
N
P
F
E
G
Rat
Rattus norvegicus
O88831
587
64428
S494
K
T
M
I
R
K
R
S
F
G
N
P
F
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519677
851
91898
G654
A
G
E
G
E
R
G
G
A
E
G
A
R
R
A
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001082316
523
58635
V448
E
H
C
T
I
V
E
V
T
E
E
E
V
K
N
Zebra Danio
Brachydanio rerio
NP_001014361
434
48727
E359
C
T
V
V
E
V
T
E
E
E
V
Q
N
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9GN62
617
69630
S508
I
L
P
I
N
L
T
S
E
A
V
L
E
R
G
Sea Urchin
Strong. purpuratus
XP_785473
661
73509
E574
Q
K
R
I
T
L
P
E
L
K
E
D
P
W
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.4
92.1
N.A.
91.8
92.5
N.A.
38.6
N.A.
53.7
52.2
N.A.
N.A.
N.A.
21.5
44.7
Protein Similarity:
100
N.A.
98.8
93.8
N.A.
94.2
94.9
N.A.
50.5
N.A.
67.3
64.1
N.A.
N.A.
N.A.
40
58.4
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
0
N.A.
0
6.6
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
6.6
N.A.
13.3
20
N.A.
N.A.
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
10
10
0
10
0
0
10
% A
% Cys:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
10
0
10
0
20
0
10
20
20
30
20
10
10
50
0
% E
% Phe:
0
0
0
0
0
0
0
0
50
0
0
0
50
0
0
% F
% Gly:
0
10
0
10
0
0
10
10
0
50
10
0
0
0
60
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
70
10
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
50
10
0
0
0
50
0
0
0
10
0
0
0
10
0
% K
% Leu:
0
10
0
0
0
20
0
0
10
0
0
10
0
0
0
% L
% Met:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
50
0
10
0
10
% N
% Pro:
0
0
10
0
0
0
10
0
0
0
0
50
10
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
10
0
50
10
50
0
0
0
0
0
10
20
0
% R
% Ser:
0
0
0
0
0
0
0
60
0
0
0
0
0
10
0
% S
% Thr:
0
60
0
10
10
0
20
0
10
0
0
0
0
0
0
% T
% Val:
0
0
10
10
0
20
0
10
0
0
20
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _